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Research teams have reported investigation of BPC-157 in models involving tendon and ligament biology, skeletal muscle and bone related endpoints, gastrointestinal mucosal integrity, and broader inflammatory signaling questions, with findings typically framed as mechanistic exploration rather than clinical outcomes.

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Jayaraj, Azimullah, Beiram, Jalal, & Rosenberg, 2019)

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reported valvular abnormalities in 24% and recommended to perform an echocardiogram at first presentation